But are biohackers a threat to national security?
That was the question lurking behind a phone call that Katherine Aull got earlier this year. Ms. Aull, 23 years old, is designing a customized E. coli in the closet of her Cambridge, Mass., apartment, hoping to help with cancer research.
She's got a DNA "thermocycler" bought on eBay for $59, and an incubator made by combining a styrofoam box with a heating device meant for an iguana cage. A few months ago, she talked about her hobby on DIY Bio, a Web site frequented by biohackers, and her work was noted in New Scientist magazine.
That's when the phone rang. A man saying he was doing research for the U.S. government called with a few polite, pointed questions: How did she build that lab? Did she know other people creating new life forms at home?
The caller said the agency he represented is "used to thinking about rogue states and threats from that," recalls Ms. Aull, a recent Massachusetts Institute of Technology graduate.
The man on the other end of the line was Nils Gilman, a researcher with Monitor 360, a San Francisco company that provides "geo-strategic" research. Mr. Gilman declined to identify his client, saying only that it's a branch of the U.S. government involved in biosecurity. "I think they want to know, is this something we need to worry about?" he said -- particularly, could the biohackers' gadgets and methods, in the wrong hands, create dangerous pathogens?